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Comparison of pain relief with clonidine, dexamethasone and dexmedetomidine as an adjuvant to local anesthetics in Femoral nerve block - which works better?

Comparison of Clonidine vs Dexmedetomidine vs Dexamethasone as an adjuvant to local anesthetic for Femoral nerve block in patient for elective anterior cruciate ligament reconstruction surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2017/08/009521
Enrollment
90
Registered
2017-08-28
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Patient having anterior cruciate ligament injury

Interventions

Intervention1: Clonidine: Femoral nerve block is performed using 30 ml of 0.25% bupivacaine with 1 mcg/kg of clonidine under combined ultrasonography and peripheral nerve stimulation guidance Control

Sponsors

Ganga Medical Centre and Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) All patients of ASA physical status I and II 2) Patient posted for elective surgical procedure

Exclusion criteria

Exclusion criteria: 1) Patient less than 18 year and more than 65 year 2) Pregnant and lactating women 3) Hemodynamically compromised patient 4) Non consenting patient/relatives refusal for procedure 5) Surgery on emergency patients with associated uncontrolled systemic disease 6) Patients in ASA physical status III and IV 7) Allergic to Medication 8) Bleeding diathesis

Design outcomes

Primary

MeasureTime frame
VAS score less than 3 (Duration of Analgesia)Timepoint: 48 Hours

Secondary

MeasureTime frame
Onset and Duration of Sensory blockade, Rescue AnalgesiaTimepoint: 48 Hours

Countries

India

Contacts

Public ContactDr J Balavenkatsubramanian

Ganga Medical Center and Hospital

sumitvaghani277@gmail.com9558000952

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026