Pain level after cleaning of root canal

Effects of HEDP in a NaOCl root canal irrigant on postoperative pain and MMP-9 levels in periapical fluid- Double Blind Randomized Control Trial - HEDP

Status

Recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2017/08/009493

Enrollment

Registered

2017-08-25

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- with dental caries

Interventions

Intervention1: HEDP: Irrigating agent Control Intervention1: NaOCl: Irrigating agent

Eligibility

Inclusion criteria

Inclusion criteria: tooth with asymptomatic apical periodontitis

Exclusion criteria

Exclusion criteria: ï?¼ Patient having pain before treatment ï?¼ Chronic condition requiring the intake of anti-inflammatory/antibiotic drugs ï?¼ Tooth which cannot be isolated by rubber dam properly ï?¼ Canal patency for periapical fluid sampling cannot be achieved ï?¼ Patient not willing to give consent

Design outcomes

Primary

Measure	Time frame
Evaluation of MMP9 markersTimepoint: 2 years	—

Secondary

Measure	Time frame
Evaluation of post irrigation pain and microbial levelsTimepoint: 2 years	—

Countries

India

Contacts

Public ContactDr Vasudev Ballal

Manipal University

drballal@yahoo.com9880626167

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026