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Comparison of the effects of three intravenous drugs (propofol,etomidate and a 1:1 mixture of propofol and etomidate) on blood pressure,heart rate during injection of study drug and on insertion of endotracheal tube inside trachea during general anaesthesia .

Comparison of propofol,etomidate and a 1:1 mixture of propofol and etomidate for hemodynamic stability and response to direct laryngoscopy and endotracheal intubation in general anaesthesia.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2017/08/009438
Enrollment
60
Registered
2017-08-21
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Inj.ETOMIDATE 2mg/ml: Inj.Etomidate 0.3mg/kg IV over 1 minute Intervention2: Inj.PROPOFOL 1% 10mg/ml: Inj.Propofol 2mg/kg IV over 1 minute Intervention3: NIL: NIl Intervention4: NIl: NI

Sponsors

Chettinad Hospital and Research InstituteKelambakkamChennai
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA I & II patients undergoing surgery under general anaesthesia

Exclusion criteria

Exclusion criteria: unwilling patients,allergy to study drug,peripheral vascular disease,pregnant patients

Design outcomes

Primary

MeasureTime frame
Hemodynamic response to study drug,intubation response to study drugTimepoint: 1 minute,3 minute and 5 minutes after injection of study drug—

Secondary

MeasureTime frame
depth of anaesthesia,incidence of pain and myoclonusTimepoint: 1 minute after injection of study drug—

Countries

India

Contacts

Public ContactArun Kumar

Chettinad Hospital and Research Institute,Kelambakkam

pugalenthi08@yahoo.co.in9489404818

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026