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To study the effect of postoperative pain following breast surgery using local anaesthestic infiltration

Study of the evaluation of postoperative analgesia after modified radical mastectomy by surgical site infiltration with either Bupivacaine alone or with Dexmedetomidine

Status
Recruiting
Phases
Phase 3Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2017/08/009401
Enrollment
60
Registered
2017-08-17
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- breast cancer

Interventions

Intervention1: study of the evaluation of postoperative analgesia after modified radical mastectomy by surgical site infiltration with either bupivacaine alone or with dexmedetomidine: to evaluate pos

Sponsors

Monisha B J Neelankavil
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: breast cancer patients undergoing modified radical mastectomy

Exclusion criteria

Exclusion criteria: Known hypersensitivity or contraindication to Bupivacaine or Dexmedetomidine; pregnancy, drug allergy, cardiac patients, renal patients, significant pulmonary diseases, bleeding diathesis, psychological, neurological, metabolic diseases,Chronic analgesic drug abuse (on oral analgesics for more than a month).

Design outcomes

Primary

MeasureTime frame
1)To compare the postoperative analgesic effects of bupivacaine following mastectomy 2)To compare the postoperative analgesic effects of dexmedetomidine following mastectomy 3)To compare the postoperative analgesic effect of Bupivacaine combined with Dexmedetomidine following mastectomy. 4)To compare the requirement of analgesics following mastectomy between the two groups for 24 hours Timepoint: visual analogue score of more than 5

Secondary

MeasureTime frame
1)To compare the postoperative analgesic effects of bupivacaine following mastectomy 2)To compare the postoperative analgesic effects of dexmedetomidine following mastectomy 3)To compare the postoperative analgesic effect of Bupivacaine combined with Dexmedetomidine following mastectomy. 4)To compare the requirement of analgesics following mastectomy between the two groups for 24 hours Timepoint: ramsay sedation scale of 2 or 3 modified aldrete score more than 9

Countries

India

Contacts

Public ContactDr Shailaja S

father muller charitable institutions

drshaila@rediffmail.com9845663466

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026