A clinical trial to study the effects of two drugs, nalbuphine and fentanyl in patients undergoing caesarean section.

To compare the effect of intrathecal nalbuphine and fentanyl as adjuvants to bupivacaine in caesarean section.

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2017/08/009399

Enrollment

150

Registered

2017-08-17

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Term Pregnant females undergoing caesarean section

Interventions

Intervention1: intrathecal fentanyl vs nalbuphine as an adjuvant to bupivacaine in caesarean section: fentanyl 20ug nalbuphine 0.8mg Control Intervention1: fentanyl: 20ug intrathecally as an adjuvant

Eligibility

Inclusion criteria

Inclusion criteria: Term Pregnant females with ASA Grade I,II

Exclusion criteria

Exclusion criteria: 1.Patientâ??s refusal 2.Any spine abnormality 3.Altered coagulation profile 4.Allergy to local anaesthetic 5.Recent myocardial infarction 6.Significant aortic stenosis Patients with neurological disorders Cardiac or respiratory system failure Any major hepatic or renal problem

Design outcomes

Primary

Measure	Time frame
Sensory blockade Motor blockade VAS Timepoint: Sensory blockade: continuouslyâ?? till onset then every 10 minutesâ?? till regression Motor blockade at 5,10,15 minutes then every 10minutes till regression 3.VAS: every 15 minutes in the first hour then hourly for 4 hours then at 12hours and 24 hours after spinal blockade	—

Secondary

Measure	Time frame
Sedation scale Complications Vitals Timepoint: Intraoperative	—

Countries

India

Contacts

Public ContactDr Tripat Kaur Bindra

GMC Patiala

tripat_noori@yahoo.co.in9501017040

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026