Will application of star anises help in improvement of various properties like antimicrobial, anti-inflammatory and astringent in oral cavity or not?

Evaluation of antimicrobial, anti-inflammatory and astringent properties of Illicium Verum in oral cavity: A double blind RCT

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2017/08/009398

Enrollment

Registered

2017-08-17

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Illicium Verum effect on oral cavity: Invitro studies had proved the antimicrobial, anti-inflammatory and astringent properties of Illicium Verum Control Intervention1: Plain distilled

Eligibility

Inclusion criteria

Inclusion criteria: 1. Fifteen healthy subjects between the age group of 18-35 years. 2. Subjects having all teeth and presenting no allergy were selected. 3. Free from systemic diseases. 4. Subjects having moderate gingival scores and fair plaque scores according to the plaque and gingival indices proposed by Silness and Loe and Loe and Silness, respectively. 5. All the index teeth should be completely erupted. 6. Should not have used mouthwashes for the last 1 month. 7. Currently non-smokers. 8. Subjects formally agreed with all study aspects and signed the consent form.

Exclusion criteria

Exclusion criteria: 1. Subjects who had been on medication in the last 6 months. 2. Suffering from any diseases which might affect the salivary flow. 3. History of antibiotic therapy in the previous 1 month till the start of the study.

Design outcomes

Primary

Measure	Time frame
Improvement in Gingival health and reduction in salivary microbial countTimepoint: 28 days	—

Secondary

Measure	Time frame
Improvement in gingival inflammation and microbial countTimepoint: 28 days	—

Countries

India

Contacts

Public ContactVikram Pal Aggarwal

Surendera Dental College and Research Institute, Sriganganagar

drvikramaggarwal@yahoo.com

Outcome results