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Study to detect shrinkage in intracranial blood vessels using brain oxygen monitoring and ultrasonography.

Observational study to evaluate the predictivity of detecting delayed cerebral ischemia after ruptured anterior cerebral artery aneurysm using transcranial cerebral oximetry and transcranial cerebral doppler.

Status
Active, not recruiting
Phases
Phase 4
Study type
Observational
Source
CTRI
Registry ID
CTRI/2017/08/009378
Enrollment
60
Registered
2017-08-16
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Patients with ruptured cerebral aneurysm i.e. subarachnoid hemorrhage. Condition varies from healthy to moribund.

Interventions

Control Intervention1: transcranial cerebral oximetry: electrodes will be applied on forehead of patient to monitor cerebral oxygenation Control Intervention2: Transcranial Cerebral doppler: Doppler t

Sponsors

Medanta The Medicity
Lead Sponsor
Dr Harsh Sapra
Collaborator
Dr Yatin Mehta
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: Adult patients with ruptured anterior cerebral circulation being treated for same at neurocritical care ICU 3 during a period of 6 months from April 2015 till Sep 2015 will be included in this study.

Exclusion criteria

Exclusion criteria: 1. Unruptured aneurysm. 2. Posterior circulation aneurysm. 3. SAH due to non-aneurysmal causes like trauma, AVM etc. 4. Patients aged 5. Patients presenting after the vasospasm window i.e after 14th day of ictus.

Design outcomes

Primary

MeasureTime frame
To compare predictivity (sensitivity and specificity) of TCCO (Transcranial cerebal oximetry) and TCD (Transcranial Doppler) in detecting DCI.Timepoint: During ICU stay of the patient within 2 weeks of the intervention

Secondary

MeasureTime frame
1 To monitor the degree of fall in rSO2 in patients with DCI. 2. To compare the difference in rSO2 between the two cerebral hemispheres. 3. To monitor the rise in velocity of MCA via TCD in patients with DCI. 4. To analyze the effect of interventions like hypertension, vasodilatation etc. on rSO2 and TCD velocities.Timepoint: 8th hourly

Countries

India

Contacts

Public ContactVarun Jain

Medanta-The Medicity

varunj2202@gmail.com9871200540

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026