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A clinical trial to study the efficiency of limited bone injury in increasing the rate of tooth movement during orthodontic treatment.

Efficiency of micro-osteoperforation assisted orthodontics on the rate of canine retraction: a split mouth randomized controlled clinical trial.

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2017/08/009331
Enrollment
28
Registered
2017-08-10
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Proclined upper incisors.

Interventions

Intervention1: Micro-osteoperforations (MOPs): Total of 6 MOPs, placed in two rows of four MOPs each, 3 mm apart, first row of three MOPs placed 2 mm distal to canine root and starting from 4 mm below

Sponsors

Dr Shivani Singh
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients undergoing fixed mechanotherapy with upper first premolar extractions requiring 5 mm or more of maxillary canine retraction. 2. Presence of full complement of teeth except third molars. 3. Fair oral hygiene.

Exclusion criteria

Exclusion criteria: Patients presenting with: 1. Previous history of orthodontic treatment. 2. Medical or systemic problems. 3. Active caries, pulpitis or periodontal disease. 4. Severe crowding (>=6mm) or severe cant of the maxillary skeletal base or palatal plane (inclination angle = 95 degrees and base plane angle =40 degrees) simultaneously existing with severely divergent or convergent facial planes (Bjork sum 400). 5. Patients exhibiting microdontia or less than 5 mm of space available for canine retraction.

Design outcomes

Primary

MeasureTime frame
Mean rate of canine retraction per month, until 2 mm or less space is present distal to canine. Measured intraorally using a digital calipers. Measured as: residual extraction space between lateral incisor (disto-gingival wing of the bracket) and canine (mesio-gingival wing of the bracket); in mm; then expressed as [(space T0-space T1)/time T0-to-T1] in mm/month. Measured by: a calibrated person, fully blinded to experimental/control side (an orthodontist).Timepoint: Measurement timing: at baseline (before space closure), at 1-month intervals; end at space closure finalization (2 mm or less space remaining distal to the canine).

Secondary

MeasureTime frame
â?¢Cumulative canine distal movement measured in mm, on pre and post dental casts. â?¢ Canine and molar rotation, tip, root resorption,bone density in HU, and alveolar bone loss to be measured on CBCT scans. â?¢ Any scars from MOPs, tooth discoloration, devitalisation or gingiva invagination will be noted. Discomfort level on VAS scale.Timepoint: At T0 and Tfinal, except, discomfort level which will be measured daily after the intervention for a week.

Countries

India

Contacts

Public ContactShivani Singh

Manipal University

emailshivanisingh@gmail.com08242428716

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026