Health Condition 1: null- Pregnant woman at term with indication for induction of labour.
Conditions
Interventions
Intervention1: Mifepristone (RU486): antiprogesterone agent causes softening and dilatation of pregnant cervix and increase in uterine activity.
Control Intervention1: dinoprostone gel: prostaglandin
Sponsors
IPGMER
Eligibility
Inclusion criteria
Inclusion criteria: 1) Postmaturity ( >40-41weeks) 2) Premature rupture of membranes. 3) Oligohydramnios. 4) Congenital malformation of the fetus. 5) Various maternal conditions( Such as- chronic hypertension and diabetes etc). 6) Bishopâ??s score
Exclusion criteria
Exclusion criteria: 1) Major Cephalopelvic disproportion. 2) Multifetal pregnancy. 3) Malpresentation. 4) Previously scarred uterus. 6)Woman who does not give informed written consent. 7) Mothers age below 18 years. 8.)Unexplained vaginal bleeding, placenta previa . 9) Medical problemâ??s like impaired renal/hepatic or adrenal function.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Vaginal delivery achieved within 48 hoursTimepoint: 48 hours | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Induction to delivery interval. 2. Bishopâ??s score improvement after 24 hours. 3. Requirement for augmentation. 4. Requirement of instrument assisted delivery or caesarean delivery. 5. Incidence of serious neonatal morbidity or perinatal mortality. 6. Incidence of serious maternal morbidity / mortality Timepoint: 48 hours | — |
Countries
India
Contacts
Public ContactDR SN BANNERJEE
IPGMER
Outcome results
None listed