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Comparison between effect of different type of intravenous fluids on blood clotting (transformation from liquid to semi-solid/solid state) in caesarean delivery (surgical procedure to deliver baby) patients using a real time monitor to measure blood clotting.

A Comparative evaluation of effect of colloid and crystalloid preloading on coagulation using thromboelastography in patients undergoing caesarean section under spinal anaesthesia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2017/08/009324
Enrollment
90
Registered
2017-08-09
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- pregnant patient without any disease posted for elective caesarean section

Interventions

Intervention1: Intravenous fluids colloids (Hydroxyethyl starch and Gelofusine): 500 ml of 10% hydroxyethyl starch given via intravenous route over 30 minutes, only once. 500 ml of Gelofusine given v

Sponsors

Deen Dayal Upadhyay Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Women with term pregnancy with a single live foetus, in age group of 20-40 years(noted as completed years) weighing 50-75 kg belonging to ASA grade I, scheduled for elective caesarean section under spinal anesthesia

Exclusion criteria

Exclusion criteria: Patient with medical co morbidity hypertension/diabetes/liver disease /cardiac disease/neurological disease, pre-existing hematological or coagulation disorder, spinal deformity, patient receiving aspirin/non steroidal anti inflammatory disease/any other anti-coagulation drug, infection over back, multiple and complicated pregnancy and patients already receiving any intravenous fluid before reaching preoperative room were excluded from the study.

Design outcomes

Primary

MeasureTime frame
To evaluate any effect on coagulation in pregnant patients on preloading with crystalloid (ringer lactate) and colloids (hydroxyethyl starch & gelofusine)Timepoint: TEG analysis was done within 01 minute of taking the sample, before fluid preloading. Fluid preloading with either Ringer Lactate, 10% HydroxyethylStarch or Gelofusine was administered over 30 minutes in the preoperative room. Blood sample was again taken after fluid pre loading, and TEG analysis done within 01 minute.

Secondary

MeasureTime frame
noneTimepoint: none

Countries

India

Contacts

Public ContactAjay Kumar

DeenDayal Upadhyay Hospital

ajayannu@gmail.com9718990114

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026