Health Condition 1: null- healthy
Conditions
Interventions
Intervention1: chemotherapy, radiotherapy, surgery: 20 patients were planned to be enrolled in this study from april 2014-October 2015. All patients were treated with 3cycles of Neoadjuvant chemother
Sponsors
NONE
Eligibility
Inclusion criteria
Inclusion criteria: 1. Muscle invasive bladder carcinoma, 2. Stage T2-T4, N0- N1,M0according to AJCC 2010 Staging. 3. Karnofsky Performance Status scale(KPS) >70. 4. All patients were explained about the protocol and a written informed consent was obtained.
Exclusion criteria
Exclusion criteria: 1. Non muscle invasive bladder carcinoma / Metastatic disease. 2. KPS 3. Significant comorbid conditions like Hypertension, Diabetes Mellitus, Coronary artery disease for more than 5 years. 4. Any other primary malignancy 5. Abnormal Haemogram: a. Haemoglobin 6. Abnormal renal function test: a. Blood urea >50mg/dl, b. Serum creatinine >1.2mg/dl.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.To assess the response rate after neoadjuvant chemotherapy. 2.To assess the response rate after radical radiation therapy. Timepoint: 6 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| .To evaluate treatment related toxicitiesTimepoint: 3 months | — |
Countries
India
Contacts
Public ContactDr Chinna Babu D
POST GRADUATE INSTITUTE OF MEDICAL EDUCATION AND RESEARCH (PGIMER)
Outcome results
None listed