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A clinical trial to study the effects of slow breathing on heart functions in pregnant women with depressive symptoms.

Effects of slow pranayamas on cardiac autonomic functions in pregnant women with depressive symptoms â?? A randomized control trial.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2017/08/009307
Enrollment
140
Registered
2017-08-09
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Slow Pranayamas: A set of slow pranayamas (Anulom-Vilom, Chandranadi, Bhramari, Sheetali) along with free hand exercises and shavashana lasting for 25 mins. To be performed daily for 8

Sponsors

JIPMER
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Pregnant women of 12-15 weeks of gestation. Women with depressive symptoms as defined by (i) Edinburgh Postnatal Depression Scale (EPDS) scores 1- 9; and (ii) those with EPDS scores 9 or more and less than 19, but current clinical depression is ruled out by Psychiatrist by use of Mini International Neuropsychiatric Interview (MINI 6.0). Able to read and understand English or Tamil.

Exclusion criteria

Exclusion criteria: Pregnant women diagnosed with major depressive disorder. Known case of psychiatric illness including depression needing pharmacological treatment. Past history of depression or maniac episode. Known cases of diabetes. Known renal disease. Known cases of hypertension, pre-eclempsia. Known cases cardiac disorders. Having multiple pregnancies. History of previous pregnancy loss due to known single gene defects, chromosomal disorders, intrauterine infections, in vitro fertilization pregnancy, previous history of intra uterine growth retardation. Known maternal structural abnormalities like kyphosis/ scoliosis. Women on any medications except for nutritional supplements. Women undergoing yoga in past one month.

Design outcomes

Primary

MeasureTime frame
Low-frequency to high frequency (LF-HF) BRS Deep Breathing Difference Heart rate and Blood Pressure Response to Standing Blood Pressure Response to Isometric Hand-grip Edinburgh postnatal depression scale. Perceived stress scores. Timepoint: start and end (8 weeks) of study

Secondary

MeasureTime frame
Nor-epinephrine hs-CRP IL-6Timepoint: start and end (8 weeks) of study

Countries

India

Contacts

Public ContactDr Shah Ziinkal Atul

JIPMER

drpravatipal@gmail.com9360682406

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026