To study the drug useful in increasing the efficacy of spinal anesthesia

Comparison of intrathecal Dexmedetomidine and Buprenorphine as adjuvant to Bupivacaine for lower limb surgeries

Status

Recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2017/08/009281

Enrollment

Registered

2017-08-07

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Posted for elective surgeries

Interventions

Intervention1: Bupivacaine 0.5% 2.5ml intrathecal once: local anesthetic used for spinal anesthesia Control Intervention1: Buprenorphine 60mcg plus bupivacaine 0.5% (h) 2.5ml via intrathecal once: Mix

Eligibility

Inclusion criteria

Inclusion criteria: 1 Patients between age 15-65yrs undergoing elective surgery . 2 ASA class I and 2.

Exclusion criteria

Exclusion criteria: 1 Patients with cardiac disease, heart block, dysarrythmia, beta blockers and alpha antagonist 2 ASA class 3 and 4. 3 Patients not wiling for spinal anaesthesia. 4 Allergy to drugs. 5 History of drug abuse, space occupying lesion, bleeding disorders.

Design outcomes

Primary

Measure	Time frame
To check which drug has better outcome as adjuvants to intrathecal BupivacaineTimepoint: FOR A PERIOD OF 2 YEARS June 2018	—

Secondary

Measure	Time frame
To monitor its effect on post operative pain reliefTimepoint: For a period of 2 years june 2018	—

Countries

India

Contacts

Public ContactDr Colaco Rohan John F R H

Father Muller Medical College

drgurumurthy@rediffmail.com9448026663

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026