Health Condition 1: null- Mandibular Fracture
Conditions
Interventions
Intervention1: Etoricoxib 90 and 120 Mg: Patients with Mandibular fracture will receive one hr before surgery
Control Intervention1: Placebo: Before surgery for Mandibular Fracture
Sponsors
All India Institute Of Medical Sciences New Delhi
Eligibility
Inclusion criteria
Inclusion criteria: 60 adult patients of 18 to 50 yrs age group, ASA grade I-II under going mandibular fracture surgery
Exclusion criteria
Exclusion criteria: 1. Known allergy, sensitivity, contraindication to Etoricoxib/NSAID 2. Patient with hypertension, asthma, bleeding disorders 3. Patient on anticoagulants 4. History of dyspepsia, pain abdomen, peptic ulcer 5. Patient with Coronary artery and peripheral vascular disease 6. Patient with cerebrovascular disorder 7. Patient with hepatic and renal impairment 8. Already on analgesics for control of pain for some other ailment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess the efficacy of oral Etoricoxib90mg and 120mg, as a pre-emptive analgesicin post operative analgesia as compared to placebo following open reduction internal fixation of mandibular fracture.Timepoint: The data will be recorded at every 1hr for the first 4 hours there after at 8th,12th and 24th hr | — |
Secondary
| Measure | Time frame |
|---|---|
| Compare patient satisfaction and side effects to EtoricoxibTimepoint: 4hrs, 8th, 12th 24 hr | — |
Countries
India
Contacts
Public ContactDevalina Goswami
Centre for Dental Education and Research
Outcome results
None listed