a clinical trial to compare efficacy of the analgesic activity of inj. Bupivacaine vs inj. Ropivacaine given at transverse abdominis block and also compare the safety parameters also.

â??Clinical evaluation of efficacy and safety of transversus abdominis plane block inj. Bupivacaine vs. inj. Ropivacaine for post operative analgesia following lower segment cesarean section: a prospective, randomized, controlled, double blind study.â??

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2017/08/009249

Enrollment

Registered

2017-08-03

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: inj. Bupivacaine: trnsverse abdominis plane block of bupivacaine 0.25% 15 ml bilaterally, Control Intervention1: inj. Ropivacaine: transversus abdominis plane block inj. ropivacaine 0.2

Eligibility

Inclusion criteria

Inclusion criteria: ï?? Informed written consent for participation in study. ï?? Age: 20-35 years ï?? Gender: Antenatal female patients scheduled for elective or non urgent lower segment cesarean section. ï?? ASA physical status I and II. ï?? Patients refusing consent.

Exclusion criteria

Exclusion criteria: 1.Contraindications to Spinal Anaesthesia like, Local infection or sepsis at the site of Lumbar puncture Bleeding disorders, thrombocytopenia Space occupying lesions of the brain Anatomical disorders of the spine Hypovolaemia e.g. following massive haemorrhage 2.Allergy to local anaesthetic drugs and NSAIDS. 3.Patient on any form of analgesics therapy. 4.BMI >= 25 kg/m2

Design outcomes

Primary

Measure	Time frame
To compare efficacy and safety of bupivacaine and ropivacaine for post operative pain relief in lower segment cesarean section with Visual Analogue Score and total dose of rescue analgesia.Timepoint: 1st day of lower cesarean section(First 24 hours after lower segment cesarean section)	—

Secondary

Measure	Time frame
Effect on hemodynamic variables like Heart Rate (HR), Mean Arterial Pressure (MAP), Oxygen saturation (SpO2). Side effects & Complications if any. Timepoint: 1st day of lower segment cesarean section (24 hours of lower segment cesarean section)	—

Countries

India

Contacts

Public ContactDr Ravikumar Parmar

Government Medical College, Bhavnagar.

ravirajparmar1@gmail.com9099097807

Outcome results