A clinical trail to evaluate the effect of Dexamethasone as an intracanal irrigant for managing postoperative pain before obturation

Dexamethasone as an intracanal irrigant for managing postoperative pain before obturation: A randomized controlled trial

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2017/08/009247

Enrollment

Registered

2017-08-03

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Vital tooth diagnosed with symptomatic irreversible pulpitis

Interventions

Intervention1: Dexamethasone sodium phosphate aqueous solution: 1mL of 4 mg/mL dexamethasone sodium phosphate aqueous solution Control Intervention1: Normal saline: Normal saline 9 g/L Sodium Chloride

Eligibility

Inclusion criteria

Inclusion criteria: older than 18 years of age Vital tooth diagnosed with symptomatic irreversible pulpitis Single visit treatment for molar tooth Patient who can understand and provide informed consent

Exclusion criteria

Exclusion criteria: Patient not willing to participate in the study, Pregnant or lactating female patient, Disabled patient Presence of radiographic evidence of periapical pathology and symptomatic adjacent tooth. Patient with recent history of trauma. Recent intake of anti-inflammatory drugs, antibiotics, or NSAIDs

Design outcomes

Primary

Measure	Time frame
Numeric pain rating scaleTimepoint: 48 hours	—

Secondary

Measure	Time frame
The dexamethasone rinse and saline rinse as an irrigant on postoperative pain will be measuredTimepoint: 48 hours	—

Countries

Nepal

Contacts

Public ContactAmit Kumar Singh

B. P. Koirala Institute of Health Sciences

ashokayer@gmail.com9842040089

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026