Health Condition 1: null- Patients of atopic dermatitis but who have chronic illness and are immunosuppressive are not recruited in the study.
Conditions
Interventions
Intervention1: Probiotics supplementation: It is a randomised controlled trial with supplementation of the probiotics to one group of atopic dermatitis patients.
Control Intervention1: Nil: This study
Sponsors
PGIMER Chandigarh
Eligibility
Inclusion criteria
Inclusion criteria: 1. Children with atopic dermatitis diagnosed according to Hanifin and Rajka between aged 6 months to 12 years. 2. All children in the above mentioned age group with be eligible irrespective of the disease severity.
Exclusion criteria
Exclusion criteria: 1. Immunocompromised chilren 2. Children with severe hepatic, renal or other systemic disease 3. 12 years of age
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. The mean difference in SCORAD in children with AD treated with conventional treatment plus probiotic supplementation versus conventional treatment alone at 0,12 and 24 weeks. 2. Mean difference in the number of days of treatment required to achieve 90% reduction in SCORAD in children with AD treated with conventional treatment plus probiotic supplementation versus conventional treatment alone. 3. Number of children with AD who relapse after stoppage of treatment at 24 weeksTimepoint: 0,12 and 24 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. To compare the IL-17 level in treatment vs control group at baseline and at 12 weeks 2. To compare the CDLQI and IDQOL at baseline and at 12 and 24 weeksTimepoint: 12, 24 weeks | — |
Countries
India
Contacts
Public ContactRicha Sharma
Post Graduate Institute Of Medical Education And Research (PGIMER)
Outcome results
None listed