Health Condition 1: null- patients suffering from active ulcerative colitis
Conditions
Interventions
Intervention1: Nano solution oral Vitamin D3: Nano preparation of oral vitamin D3. 5ml of this solution which contains 60,000 I.U.will be taken orally on empty stomach once daily for 8 days only.
Con
Sponsors
PostGraduate Institute of Medical Education and Research
Eligibility
Inclusion criteria
Inclusion criteria: Patients suffering from active ulcerative colitis
Exclusion criteria
Exclusion criteria: 1.Inability to obtain written informed consent 2.Pregnant or lactating women 3.Patients with life threatening, cardiac, renal or pulmonary disease. 4.Severe disease requiring hospitalization. 5. Patients already supplemented with vitamin D
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| i. Response is defined as reduction of at least 3 points in the disease activity index (UCDAI) from the baseline value at 4 weeks. ii. Reduction in the stool frequency by 2/day iii. Improvement in stool consistency (Bristol score) by 2 points Timepoint: 4 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| Remission 1. Remission is defined as achieving UCDAI score less than 3 at 4 weeks 2. Reduction of Fecal Calprotectin by 50 units 3. Reduction of endoscopic and histological markers of inflammation 4. Improvement in quality of lifeTimepoint: 4 weeks | — |
Countries
India
Contacts
Public ContactRizwan Ahamed Z
PostGraduate Institute of Medical Education and Research, Chandigarh
Outcome results
None listed