Health Condition 1: null- Chronic Periodontitis Health Condition 2: M272- Inflammatory conditions of jaws
Conditions
Interventions
Intervention1: Vitamin D tablets: 2000IU vitamin D tablets daily for 3 months
Control Intervention1: Subjects who have not been prescribed Vitamin D: Subjects undergoing only scaling and root planing
Sponsors
Rajiv Gandhi University of Health Sciences
Eligibility
Inclusion criteria
Inclusion criteria: Inclusion Criteria : 1.Study subjects should be >25 years of age. 2.Patients suffering from chronic periodontitis i.e. a)Bleeding on probing b)Probing pocket depth of >= 5 mm c)Clinical attachment loss of >= 3 mm 3.Patients should be vitamin D sufficient (serum levels 30ng/ml and above) according to vitamin D council. 4.Systemically healthy individuals with minimum 20 teeth in occlusion.
Exclusion criteria
Exclusion criteria: Exclusion Criteria: 1.Patients with systemic diseases that can impair immune response such as diabetes mellitus, HIV, immunological disorder and hepatitis. 2.Patients on any systemic antibiotics, NSAIDS, steroid therapy and any other drugs which is known to affect the periodontal status. 3.Smokers and former smokers are excluded from the study. 4.Patients who have received periodontal treatment in the preceding year or who have taken antibiotics within the previous 3 months. 5.Pregnant or lactating women and those taking oral contraceptive drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Increase in GCF cathelicidine levels.Timepoint: 90 days. | — |
Secondary
| Measure | Time frame |
|---|---|
| Improvement in epithelial barrier functionTimepoint: 90 days | — |
Countries
India
Contacts
Public ContactDr Aditi Bose
Sri Rajiv Gandhi College of Dental Sciences and Hospital
Outcome results
None listed