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A clinical trial to study the effects of two anesthetic techniques while motor evoked potential monitoring during spine surgery

Effect of two anesthetic regimes with dexmedetomidine as adjuvant on transcranial electrical motor evoked potentials during spine surgery: a pilot study.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2017/08/009191
Enrollment
30
Registered
2017-08-01
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G549- Nerve root and plexus disorder, unspecified

Interventions

Intervention1: Desflurane: inhalational agent desflurane less than 0.5 MAC along with intravenous infusion of dexmedetomidine 0.6 mcg/kg/hr and fentanyl 1 mcg/kg/hr as adjuvant. Total duration of ther

Sponsors

AIIMS
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA Grade I-II of either sex presenting for spine surgery with motor evoked potential monitoring

Exclusion criteria

Exclusion criteria: preoperative neurologic deficit grade pre-existing myopathies morbid obesity, diabetes mellitus history of coronary artery disease, history of chronic renal and hepatic insufficiency, history of heart block, history of allergy to any drugs, history of seizures history of pacemaker and automatic implantable cardioverter-defibrillator

Design outcomes

Primary

MeasureTime frame
To study the effect of two anaesthetic regimes with dexmedetomidine as adjuvant on transcranial electrical motor evoked potentials during spine surgery Timepoint: Baseline (T0) TcMEPs amplitudes will be recorded before incision.T1(at 30 min), T2(at 60 min),T3(at 90 min),T4(at 120 min). The values will be recorded hourly thereafter till the end of surgery.—

Secondary

MeasureTime frame
To study the effect of two anaesthetic regimes with dexmedetomidine as adjuvant on stimulation protocol needed to elicit recordable repeatable amplitudes transcranial electrical of motor evoked potentials during spine surgery Timepoint: Baseline (T0) TcMEPs amplitudes will be recorded before incision.T1(at 30 min), T2(at 60 min),T3(at 90 min),T4(at 120 min). The values will be recorded hourly thereafter till the end of surgery.—

Countries

India

Contacts

Public ContactRajeeb Kumar Mishra

AIIMS

prabhakaraiims@yahoo.co.in9868398205

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026