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Intra nasal drug (Dexmedetomidine) to prevent tachycardia and hypertension response to anesthetic induction (laryngoscopy and intubation) in adults

A randomized controlled trial of intra nasal Dexmedetomidine in attenuation of hemodynamic response to laryngoscopy and intubation in adults

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2017/07/009180
Enrollment
90
Registered
2017-07-31
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- patients coming for elective surgeries Health Condition 2: R00-R99- Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified

Interventions

Intervention1: INTRA-NASAL Dexmetedomidine 1 microg/kg and 2 microg/kg: INTRA-NASAL Dexmetedomidine 1 microg/kg (Group D1) and 2 microg/kg (Group D2)will be given as pre-medication, and its effects w

Sponsors

HIMSR HAHC Hospital Delhi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA I, patients undergoing elective surgery under general anaesthesia with endo-tracheal intubation

Exclusion criteria

Exclusion criteria: Any nasal pathology, known allergy to drugs in use, Difficult airway, Pregnancy

Design outcomes

Secondary

MeasureTime frame
Sedation level baseline and 30 minutes after pre-medicatin, Dose of induction agent (PROPOFOL)for anesthesia induction, Side effects,if anyTimepoint: Sedation score will be recorded baseline and 30 minutes after pre-medication—

Primary

MeasureTime frame
hemodynamic response to laryngoscopy and intubationTimepoint: Baseline and 1,3,5 & 10 minutes of laryngoscopy and intubation—

Countries

India

Contacts

Public ContactAnjali Kochhar

Jamia Hamdard

kochharanjali0@gmail.com9999197721

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026