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A clinical trial to study the effects Limited access dressing in patients with Diabetic ulcers.

Biochemical study of granulation tissues modulated by negative pressure under LAD in Diabetic wounds

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2017/07/009147
Enrollment
50
Registered
2017-07-27
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Diabetic Ulcers

Interventions

Intervention1: Limited access dressing: Negative pressure wound therapy and moist wound healing. Each LAD dressing can keep upto 10-15 days and Wounds were washed with saline daily through the ports w

Sponsors

Manipal University
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Diabetic wounds

Exclusion criteria

Exclusion criteria: Patients with collagen disorders, Leprosy patients, Pregnant women, Liver cirrhosis, HIV +ve patients.

Design outcomes

Primary

MeasureTime frame
Collagen content (Hydroxyproline) in the granulation tissueTimepoint: zero day and 10th day—

Secondary

MeasureTime frame
hexosamine, total protein, and antioxidants [reduced glutathione (GSH), glutathione peroxidase (GPx), glutathione s-transferase (GST), catalase (CAT), thiol], wound surface pH, matrix metalloproteinase-2 (MMP-2), and oxidative biomarker malondialdhyde (MDA) were measured in the granulation tissue of diabetic woundsTimepoint: After 10 days of treatment—

Countries

India

Contacts

Public ContactDr Pramod Kumar

Kasturba Medical college and Hospital, Manipal, Karnataka, India

honnegowda33@gmail.com918453881779

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026