Skip to content

Structural Changes In Crystals In Urine Of Calcium Oxalate Stone Patients With Changes In Diet.

Effect Of Dietary Modifications On The Morphology Of Calcium Oxalate Crystals And Corresponding Changes In The Optical Density Of Urine Of Patients With Calcium Oxalate Stones In The Urinary Tracts.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2017/07/009143
Enrollment
60
Registered
2017-07-27
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Patients with calcium oxalate stones in the urinary tract

Interventions

Intervention1: High Calcium diet followed by High Oxalate diet.: Dose: 200 ML. Milk + 2 calcium tablets + bland diet for breakfast followed four hours later by high oxalate diet for lunch. Frequency :

Sponsors

Kerala State Council For Science Technology and Environment
Lead Sponsor
Government MeDical College Thiruvananthapuram
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: Patients who have been diagnosed with calcium oxalate urinary stones

Exclusion criteria

Exclusion criteria: 1.Patients who do not have calcium based urinary stones( such as uric acid, cystine, struvite) 2. Patients with obstructive uropathy , chronic urosepsis,/ positive urine culture , Renal failure, Renal tubular acidosis, Primary hyper oxaluria, Medullary sponge kidney 3. Less than 19 years 4. Patients with abnormalities of the urinary tracts 5. Serious diseases 6. Pregnancy 7. Active cancer 8. Recurrent Urinary tract infection 9. Gross hematuria 10.Inability to give informed consent

Design outcomes

Primary

MeasureTime frame
1. To determine the in vitro morphological changes in calcium oxalate crystals in native urine of patients and corresponding variation in the optical density of urine as a function of in vitro super saturation of these urine samples following dietary modificationsTimepoint: Four hours after diet intake

Secondary

MeasureTime frame
1. To determine the in vitro morphological changes in calcium oxalate crystals in native urine of patients and corresponding variation in the optical density of urine as a function of in vitro super saturation of these urine samples following dietary modifications after a period of two monthsTimepoint: Two months

Countries

India

Contacts

Public ContactDr Jim Joe

Government Medical College, Kottayam

drjimjoe@gmail.com9544156643

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026