Health Condition 1: null- to study the incidence and severity of postoperative nausea and vomiting in female patients undergoing thyroidectomy or mastectomy
Conditions
Interventions
Intervention1: capsule Aprepitant: Cap. Aprepitant 40mg single dose was given orally within 1 hour preoperatively along with the pre medication and
Inj. Placebo 4 ml IV was given in the post operativ
Sponsors
Christian medical college
Eligibility
Inclusion criteria
Inclusion criteria: American Society of Anaesthesiology physical status 1 and 2 Female patients Age 18 to 65 years Scheduled for thyroidectomy or mastectomy
Exclusion criteria
Exclusion criteria: Patients who are receiving antiemetics Patients on steroid medication Patients on drugs known to cause emesis currently or in the immediate past Patients with known hypersensitivity to ondansetron or aprepitant Pregnant and nursing mothers
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of post operative vomitingTimepoint: Incidence of post operative vomiting during the first 24 hour postoperative period | — |
Secondary
| Measure | Time frame |
|---|---|
| Severity of post operative nausea, number of episodes of vomiting, timing of the first vomiting episode, use of rescue antiemeticsTimepoint: 24 hour postoperative period | — |
Countries
India
Contacts
Public ContactSalome Jeyabalan
Christian medical college
Outcome results
None listed