Health Condition 1: null- chronic rhinosinusitis
Conditions
Interventions
Intervention1: dexmedetomidine and esmolol: used for intervention to reduce the haemodynamic response to laryngoscopy and endotracheal intubation
Control Intervention1: dexmedetomidine: Loading dose o
Sponsors
Dr Veeresh
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients aged 18 - 60 years of age of either gender 2. ASA physical status I or II 3. Elective cases under general anaesthesia 4. Patients with unanticipated difficult airway ( mallampatti score 1 and 2 )
Exclusion criteria
Exclusion criteria: 1. Patients on beta-blockers, alpha-2 agonists or any other cardiac medications 2. Patients with known history of allergy to the study drugs 3. Pregnant and lactating patients 4. ASA grade III and IV 5. Unwilling patients 6. Preoperative ECG changes such as arrhythmias, bradycardia (HR 7. Patients with anticipated difficult airway i.e. Mallampati class III & IV, mouth opening less than two finger breadth, restricted neck extension, cervical spondylosis 8. More than 1 attempt to intubate patients
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| heart rate and mean arterial pressureTimepoint: Every 5 min for the first 1 hr followed by every 15 min for next 2 hrs. | — |
Secondary
| Measure | Time frame |
|---|---|
| nilTimepoint: - | — |
Countries
India
Contacts
Public ContactDr Lulu Sherif
Father Muller Medical College ,Mangalore
Outcome results
None listed