Nalbuphine as an addition to Bupivacaine in Supraclavicular block for Upper Limb Orthopedic Surgeries.

â??Clinical evaluation of Nalbuphine as an adjuvant to local anaesthetic in Supra Clavicular Brachial Plexus Block for Upper Limb Orthopedic Surgeris: A Prospective, Randomized, Double Blind Study.â??

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2017/07/009057

Enrollment

100

Registered

2017-07-17

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- patients posted for upper limb orthopaedic surgery of 18 to 60 yrs of age belonging to ASA I and II

Interventions

Intervention1: Bupivaciane, nalbuphine: DOSE-Bupivacaine(0.5%)25 ml nalbuphine 20 mg DILUTED UPTO 5 ML OF NORMAL SALINE FREQUENCY-SINGLE TIME ROUTE- SUPRACLAVICULAR BRACHIAL PLEXUS BLOCK DURATION-24 H

Eligibility

Inclusion criteria

Inclusion criteria: Informed written consent for participation in study. Gender: Either gender. Patients scheduled for elective upper limb orthopedic surgery ASA physical status I and II. BMI

Exclusion criteria

Exclusion criteria: 1.Patients refusing consent. 2.Contraindications to regional anesthesia: Previous nerve injury. History of drug dependence/abuse. History of drug allergy. Allergic to local anaesthetics. Patients taking analgesics and sedatives. Patients on anticoagulants. History of bleeding disorders. Psychiatric illness. Uncooperative patients. 3.Any major systemic illness like hypertension, heart block etc. 4.Antenatal females and lactating mother. 5.Inadequate effect requiring supplementation. 6.ASA physical status III and above.

Design outcomes

Primary

Measure	Time frame
1.Onset, peak and duration of sensory blockade. 2.Onset, peak and duration of motor blockade. 3.Duration of effective post-operative analgesia. 4.Total dose and frequency of rescue analgesics required in 24 hours. 5.Ramsey Sedation score.Timepoint: baseline and than 1 min,3 min,5 min,10 min,15 min,30 min, 1 hour,2 hour, 3 hour, 4 hour and every 2 hourly till 24 hours after brachial block Secondary	—

Measure

Time frame

1.Onset, peak and duration of sensory blockade. 2.Onset, peak and duration of motor blockade. 3.Duration of effective post-operative analgesia. 4.Total dose and frequency of rescue analgesics required in 24 hours. 5.Ramsey Sedation score.Timepoint: baseline and than 1 min,3 min,5 min,10 min,15 min,30 min, 1 hour,2 hour, 3 hour, 4 hour and every 2 hourly till 24 hours after brachial block Secondary

—

Secondary

Measure	Time frame
1.Effects on hemodynamic variables Heart Rate, Mean Arterial Blood andperipheral oxygen saturation.Timepoint: baseline and than 1 min,3 min,5 min,10 min,15 min,30 min, 1 hour,2 hour, 3 hour, 4 hour and every 2 hourly till 24 hours after brachial block	—

Countries

India

Contacts

Public ContactDr Komal Shah

Govt. Medical College And Sir Takhtsinhji Hospital, Bhavnagar

shah.komal@rediff.com9913517989

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026