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Testing analgesic efficiency of two medications in orthopaedic surgeries.

Preemptive analgesic efficacy of intravenous diclofenac versus IV paracetamol in orthopedic surgeries: A prospective randomized, double blind, controlled study.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2017/07/009049
Enrollment
100
Registered
2017-07-14
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- The study was conducted in 100 ASA physical status grade I and II, of either sex, between the age group of 18-65 years scheduled for elective upper limb orthopedic surgeries

Interventions

Intervention1: Group D: group D patients were given intravenous 75 mg diclofenac (inj. Dynapar AQTM) diluted in 100 ml 0.9% NS also wrapped by opaque sheet, 30 min before surgery. Control Intervention

Sponsors

St Stephens Hospital committee
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: The study was conducted in 100 ASA physical status grade I and II, of either sex, between the age group of 18-65 years scheduled for elective upper limb orthopedic surgeries under general anesthesia (GA). Patients were admitted at least 24 hours before surgery. Detailed history, examination and relevant investigations like complete blood count, renal/liver function tests, coagulation profile, X-ray chest and ECG were carried out. Patients posted for unilateral or bilateral upper limb surgery e.g., shoulder, humerus and elbow surgery were included

Exclusion criteria

Exclusion criteria: Patients allergic reaction to study drugs, gastric ulcer complaints for last 6 months, coagulopathy, alcohol or drug addicts, neurological or psychiatric illness and clinically significant major organ disease were excluded from the study.

Design outcomes

Primary

MeasureTime frame
Pulse rate, blood pressure, and oxygen saturation were recorded intraoperatively and after extubation. Intraoperative pain was assessed by hemodynamic parameters (inadvertent rise in HR, BP) while postoperative pain assessment using visual analog score (VAS) ranging from 0-100 mm was done postoperative complication was noted and treated accordingly. Timepoint: Pulse rate, blood pressure, and oxygen saturation were recorded 5 minutes before induction and every 10 minutes intraoperatively and after extubation. Intraoperative pain was assessed by hemodynamic parameters (inadvertent rise in HR, BP) while postoperative pain assessment using visual analog score (VAS) ranging from 0-100 mm was done postoperative complication was noted and treated accordingly.

Secondary

MeasureTime frame
any postoperative complication was noted and treated accordingly.Timepoint: AFTER EXTUBATION (GA).at 15 min, 30min, 1 hr, 2hrs, 4hrs and 6hrs

Countries

India

Contacts

Public ContactDr Grace Cherian

St. Stephens Hospital

spunkygst@gmail.com9716700197

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026