A randomized control clinical trial to evaluate the efficacy of 2 bio resorbable matrices in apexification procedure.

To evaluate and compare apexification procedure with and without the use of extra radicular matrices.

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2017/07/009029

Enrollment

Registered

2017-07-12

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Non vital permanent teeth in otherwise healthy dental child patients

Interventions

Intervention1: Platelet-rich fibrin (PRF): Platelet-rich fibrin (PRF) or leucocyte- and platelet-rich fibrin (L-PRF) is a second-generation PRP where autologous platelets and leucocytes are present in

Eligibility

Inclusion criteria

Inclusion criteria: Child patients with non vital young permanent teeth with open apices, secondary to caries or trauma, indicated for endodontic treatment.

Exclusion criteria

Exclusion criteria: Patients with known allergy to any of the dental materials to be used. Tooth with root fracture, unrestorable remaining crown structure, internal or external root resorption, systemic conditions, syndromes and congenital malformation.

Design outcomes

Primary

Measure	Time frame
Complete control and resolution of signs and symptoms of pain, swelling, fistula, mobility and absence of tenderness on percussion.Timepoint: Follow up at 6 and 12 months	—

Secondary

Measure	Time frame
Absence of Periapical bone loss, radiographic healing of periapical lesion.Timepoint: 12 months	—

Countries

India

Contacts

Public ContactAysha Siddiqui

King Georges Medical University

richa.bahal@gmail.com9936038511

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026