A trial to study the effects of prophylactic use of Tranexamic acid in reducing blood loss after normal vaginal delivery

Effect of prophylactic use of tranexemic acid in post partum blood loss after normal vaginal delivery

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2017/07/009011

Enrollment

273

Registered

2017-07-10

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Tranexamic acid: Tranexamic acid 1gm iv slowly over 10 min after the delivery of the fetus Intervention2: Nil: Routine uterotonic agents given Control Intervention1: Nil: Nil

Eligibility

Inclusion criteria

Inclusion criteria: Age > 20 yrs Term pregnancies >37 wks Singleton pregnancies Planned vaginal deliveries

Exclusion criteria

Exclusion criteria: Age 35 yrs Pre eclampsia,multiple pregnancy,placental abnormalities Instrumental deliveries Any cardiovascular, renal, liver disorders Any hematological , hemorrhagic disorders H/o venous or arterial thrombosis H/o use of LMWH or antiplatelet drugs

Design outcomes

Primary

Measure	Time frame
Mean change in peripartum hemoglobin and hematocrit values in the two groups Timepoint: After 24 hrs of Delivery	—

Secondary

Measure	Time frame
â?¢ Requirement of use of additional uterotonic agents to control blood loss in the two groupsTimepoint: Within 24 hrs;To compare the incidence of PPH in control and test armTimepoint: Within first 6 hrs	—

Countries

India

Contacts

Public ContactDr Tony Jose

Armed Forces Medical College

ltcoltony@gmail.com7875674889

Outcome results