Health Condition 1: null- All patients diagnosed with Hepatic Encephalopathy presenting to the inpatient care at the department of Gastroenterology, IMS, BHU. Health Condition 2: K746- Other and unspecified cirrhosis ofliver
Conditions
Interventions
Intervention1: Polyethylene glycol: 3 to 4 L of PEG administered orally or via nasogastric tube, PEG will be administered in a single dose over 4 â?? 6 hours. It will be given until patients/ Legall
Sponsors
Institute of Medical Sciences
Eligibility
Inclusion criteria
Inclusion criteria: 1. All patients diagnosed with Hepatic Encephalopathy presenting to the inpatient care at the department of Gastroenterology, IMS, BHU 2. Age 18 to 80 years 3. Diagnosis of Chronic Liver Disease from any cause 4. The availability of a Legally Authorized Representative for interview and consent
Exclusion criteria
Exclusion criteria: 1. Patients with Hepatic Encephalopathy Grade I and Grade IV. 2. Acute Liver failure 3. More than 1 dose of lactulose before consent 4. No Legally Authorized Representative to give consent/ Refusal of consent 5. Previously recruited in the present study 6. Serum Creatinine more than 2.5 mg /dl 7. Treated with Vasopressors 8. Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement in HESA ScoreTimepoint: 24 Hours | — |
Secondary
| Measure | Time frame |
|---|---|
| Deterioration in HESA Score, Refusal, Discharge or DeathTimepoint: 24 hours and Within a week after recruitment | — |
Countries
India
Contacts
Public ContactDr Sunit Kumar Shukla
IMS, BHU, Varanasi UP
Outcome results
None listed