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Comparison between two pain reducing technique after operation

A comparison of two techniques of postoperative analgesia: lignocaine-fentanyl intravenous infusion and ropivacaine-fentanyl epidural infusion in patients undergoing major abdominal oncosurgery- a randomized control trial.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2017/07/008987
Enrollment
60
Registered
2017-07-06
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- With diagnosis of abdominal malignancy

Interventions

Intervention1: Group IV: IV lignocaine and fentanyl infusion Control Intervention1: Group EPI: Epidural Ropivacaine and fentanyl infusion

Sponsors

AIIMS
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Age of 18 years or older, but less than 70 years. 2. Clinical diagnosis of primary abdominal malignancy. 3. Agree to receive postoperative patient-controlled analgesia. 4. Agree to participate in the study and have signed written informed consent.

Exclusion criteria

Exclusion criteria: 1. Complicated with mental illness, severe heart disease (NYHA classification 3), any renal or hepatic disorder before surgery. 2. Contraindications of epidural anesthesia. 3. Allergic to any drug used during the study. 4. Patients who are likely to be electively ventilated in postoperative period.

Design outcomes

Primary

MeasureTime frame
Rescue analgesia in post operative periodTimepoint: Rescue analgesia in post operative period

Secondary

MeasureTime frame
Post operative pain scoreTimepoint: 1,2,4,8,12,18,24 hrs post operative period.

Countries

India

Contacts

Public ContactDr Rudranil Nandi

All India Institute of Medical Sciences

seemamishra2003@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026