Drugs for control of fits in children

Comparison of Levitiracetam as second line drug in place of Fosphenytoin in Status epilepticus among children

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2017/07/008980

Enrollment

170

Registered

2017-07-05

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- status epilepticus in children

Interventions

Intervention1: levetiracetam: 20mg/kg intravenously over 20 minutes Control Intervention1: fosphenytoin: 20mg/kg intravenously over 20 minutes

Eligibility

Inclusion criteria

Inclusion criteria: all consecutive children admitted with status epilepticus in PICU with seizures refractory to two doses of midazolam

Exclusion criteria

Exclusion criteria: children who are loaded with drugs other than two doses of midazolam , pre-hospital therapy and with shock

Design outcomes

Primary

Measure	Time frame
clinical cessation of seizuresTimepoint: from the time of administration of the drug	—

Secondary

Measure	Time frame
seizure recurrence within 12 hoursTimepoint: 12 hours	—

Countries

India

Contacts

Public ContactDr V Poovazhagi

Government Omandurar Estate Block B

poomuthu@gmail.com9840033020

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026