Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Group A: Group A will receive a single administration of oral Pregabalin 75 mg,one hour prior to Spinal anesthesia
Control Intervention1: Group B: Group B will receive a single administ
Sponsors
Azeezia Medical College
Eligibility
Inclusion criteria
Inclusion criteria: Patients of either sex,between age 18 years-65years,ASA physical status 1-2,who are scheduled for infraumbilical laprotomy under Spinal Anesthesia and are willing and able to give informed consent will be recruited to the trial
Exclusion criteria
Exclusion criteria: Patients with 1.known drug allergy to pregabalin 2.uncontrolled hypertension 3.uncontrolled diabetes mellitus 4.ischemic heart disease 5.cerebrovascular disease 6.renal and hepatic disease 7.history of alcohol and drug abuse 8.any general contraindications for spinal anaesthesia 9.chronic pain and neurological disorders 10.on NSAIDâ??s and on other analgesics 11.Pregnancy and lactation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 24 hour total rescue analgesic (diclofenac +/-pentazocine) consumptionTimepoint: At 24 hours post operatively. | — |
Secondary
| Measure | Time frame |
|---|---|
| Reduction of postoperative pain scores,Time to first requirement of rescue analgesia, Recovery time from sensory block and Tolerability of the used doses represented by the side effects.Timepoint: at 4,8,12,16,20 and 24 hours post operatively. | — |
Countries
India
Contacts
Public ContactDR DERLIN THOMAS
Azeezia Medical College Hospital,Kollam
Outcome results
None listed