Health Condition 1: null- ASA I and II patients 18 to 60 years of age scheduled to undergo unilateral upper limb surgery under ultrasound-guided supraclavicular brachial plexus block will be enrolled in the study Health Condition 2: V899- Person injured in unspecified vehicle accident
Conditions
Interventions
Intervention1: Group I: Patients will be administered unilateral ultrasound-guided supraclavicular brachial plexus block using 25ml of 0.375% Bupivacaine with 8mg (2ml) of dexamethasone. Isotonic sa
Sponsors
Department of Science and Technology
Eligibility
Inclusion criteria
Inclusion criteria: 1. 30 ASA I and II patients 2. 18 to 60 years of age 3. Patients scheduled to undergo unilateral upper limb surgery under ultrasound-guided supraclavicular brachial plexus block
Exclusion criteria
Exclusion criteria: 1. Age 60 years 2. Body mass index = 35kg/m2 3. Inability to consent to the study 4. Local infection at the puncture site 5. Allergies / contraindications to any of the drugs used in the study 6. History of endocrine diseases 7. Significant cognitive or psychiatric disease 8. Coagulopathy 9. Systemic glucocorticoid use 10. Routine use of opioid medications 11. Diabetes 12. Chest or shoulder deformities on the operative side 13. Pre-existing neurological disease or neuropathy in the upper extremities 14. Regional block refusal / contraindication 15. Inability to understand the scoring systems to be used in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate the blood levels of Dexamethasone after its administration either perineurally or intravenously.Timepoint: Blood samples will be taken before drug administration (baseline value, time point zero) and at 20, 40 and 60 min, and 2, 4, 8 and 12 hours after Dexamethasone administration | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Postoperative NRS scores 2. Time to first request for rescue analgesic 3. Total analgesic consumption in the first 24 postoperative hours 4. Time to return of full motor power in the operated limb 5. Any adverse or side effects of study drugs Timepoint: on admission to the PACU and then at 1h, 2h, 4h, 8 h, 12 h, 18 h and at 24 hour interval | — |
Countries
India
Contacts
Public ContactDr Nidhi Bhatia
Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh
Outcome results
None listed