Health Condition 1: M262- Anomalies of dental arch relationship Health Condition 2: null- Dental Malocclusions undergoing Orthodontic Treatment
Conditions
Interventions
Intervention1: In situ gel periodontal injection of 1,25-(OH)2D3: 0.2ml dimethyl sulphoxide (DMSO)based in situ gel containing strength of 250pg/ml of 1, 25 dihydroxy-cholecalciferol was given at mont
Sponsors
Dr Sanju Thomas Varughese
Eligibility
Inclusion criteria
Inclusion criteria: 1) All subjects with average growth pattern, 2) All subjects with Class I or Class II malocclusion indicated for bilateral maxillary first premolar extraction 3) All subjects with a minimum of 5mm of extraction space available before maxillary permanent canine distalization 4) All subjects undergoing treatment with Pre-adjusted Edgewise Appliance (PEA) with 0.022 MBT prescriptions and 5) All subjects who have finished with leveling and alignment (1st Phase).
Exclusion criteria
Exclusion criteria: 1) Previous history of orthodontic or orthopaedic treatment, 2) Presence of craniofacial anomalies, 3) Presence of any signs and symptoms of gingival and periodontal diseases 4) Presence of significant medical history (including drug allergy) or medications that would adversely affect the development or structure of the teeth and jaws and any subsequent tooth movement and 5)Pregnant and lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rate of canine retraction Timepoint: Measured in millimeters at monthly intervals | — |
Secondary
| Measure | Time frame |
|---|---|
| Bone Density changes in HU Anchorage loss in millimetersTimepoint: Measured at monthly intervals | — |
Countries
India
Contacts
Public ContactDr Sanju Thomas Varughese
Rajiv Gandhi University Of Health And Allied Science (RGUHS Karnataka),recognised by DCI
Outcome results
None listed