Comparison of MRI grading of lumbar disc prolapse and outcome of lumbar epidural steroid injection

Lumbar epidural steroid injection: Correlation between size and location of lumbar disc herniation and efficacy of steroid injection

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2017/06/008897

Enrollment

Registered

2017-06-22

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M472- Other spondylosis with radiculopathy Health Condition 2: null- patients with low back pain

Interventions

Intervention1: Lumbar epidural steroid injection: Patients will receive lumbar epidural steroid injection with Methylprednisolone Acetate Injectable Suspension (depomedrol) 80 MG under fluoroscopic gu

Eligibility

Inclusion criteria

Inclusion criteria: 1.Low back pain with radiation for at least 3 months duration not responding to medication and physical therapies. 2.MRI evidence of disc herniation

Exclusion criteria

Exclusion criteria: 1.Patient with history of surgery on lumbar spine 2.Allergic to contrast dye or steroid 3.Bleeding diathesis 4.Pathologica cause of spine disease 5.Patient who received lumbar edpiural steroid injection in past three months or is using systemic steroid for pain relief 6.Pregnant patient

Design outcomes

Primary

Measure	Time frame
Co-relation between type of disc herniation and patient related outcome measures like 1.Visual Analogue Scale (VAS) for back and leg pain 2.Disease- specific physical disability Modified Oswestry Disability Index (MODI) 3)Preference-based health status- EuroQol-5D (EQ-5D) 4)SF-12 Health Survey Score Timepoint: Patients in each group will be followed up for a period of three months at an interval of 2 weeks, 1 month, 6 weeks, 10weeks, 3 months. Patients who get less than 50% pain relief from baseline will receive additional injection with same volume at least 15 days apart with maximum of 3 injections. Those who had more than 50% pain relief will not receive further injection till pain increases to 50% of baseline again.	—

Measure

Time frame

Co-relation between type of disc herniation and patient related outcome measures like 1.Visual Analogue Scale (VAS) for back and leg pain 2.Disease- specific physical disability Modified Oswestry Disability Index (MODI) 3)Preference-based health status- EuroQol-5D (EQ-5D) 4)SF-12 Health Survey Score Timepoint: Patients in each group will be followed up for a period of three months at an interval of 2 weeks, 1 month, 6 weeks, 10weeks, 3 months. Patients who get less than 50% pain relief from baseline will receive additional injection with same volume at least 15 days apart with maximum of 3 injections. Those who had more than 50% pain relief will not receive further injection till pain increases to 50% of baseline again.

—

Secondary

Measure	Time frame
naTimepoint: na	—

Countries

India

Contacts

Public ContactDR SEKAR L

PGIMER, CHANDIGARH

jeet1516@gmail.com7087009510

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026