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Xylitol or CPP-ACP, which is the better caries preventive agent?

Effectiveness of Casein Phosphopeptide Amorphous Calcium Phosphate and Xylitol Chewing Gums on the salivary pH, Buffer Capacity and Streptococcus mutans count â?? An Interventional Study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2017/06/008895
Enrollment
20
Registered
2017-06-22
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Caesin Phosphopeptide Amorphous Calcium phosphate: delivered as chewing gum available over the counter as Recaldent. Recommended to use it thrice daily after each meal for a period of 1

Sponsors

Sri Venkateswara dental College and Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 20 healthy individuals in the age group 18 to 25years without any active caries lesion

Exclusion criteria

Exclusion criteria: 1.Individuals who were regular users of CPP-ACP or Xylitol gums 2.Individuals with systemic conditions 3.Individuals who were on antibiotics in the last 2 weeks 4.Individuals who were allergic to these gums

Design outcomes

Primary

MeasureTime frame
Salivary pH, Buffer Capacity and Streptococcus mutans CountTimepoint: values at baseline, 24hours and after 2 weeks were taken—

Secondary

MeasureTime frame
NilTimepoint: Nil—

Countries

India

Contacts

Public Contactpoorni s

Sri Venkateswara Dental college

poorniis@yahoo.com9941123738

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026