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Gargles to reduce sore throat after anaesthesia

Comparative evaluation of efficacy of magnesium sulphate and ketamine gargles on prevention of post-operative sore throat following Proseal laryngeal mask airway insertion

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2017/06/008871
Enrollment
75
Registered
2017-06-20
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- patients of 18 to 60 years of age requiring general anaesthesia

Interventions

Intervention1: magnesiumsulfate: Magnesium sulfate gargles was prepared by adding 2.4ml (1.2g) of magnesium sulfate, 24ml of dextrose 25% and 3.6ml normal saline 0.9% (total volume 30 ml). Patients p

Sponsors

Maulana Azad Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients requiring general anaesthesia with Proseal laryngeal mask airway. 2. Physical status ASA grade I and II

Exclusion criteria

Exclusion criteria: 1. Patients with history of pre-operative sore throat, asthma, COPD. 2. Patients requiring oropharyngeal, head and neck surgeries. 3. Patients with Body Mass Index > 30 kg/m2. 4. Patients with full stomach or abdominal distension. 5. Patients with gastroesophageal reflux disease. 6. Patients with modified mallampatti class IV, anticipated difficult airway. 7. Patients having allergy to study drugs. 8. Patients who have recently received NSAIDS. 9. Patients having nausea and vomiting. 10. Expected duration of surgery more than 2 hours.

Design outcomes

Secondary

MeasureTime frame
1. severity of post-operative sore throat 2. oral / pharyngeal trauma 3. side effects of drugs like nausea, vomiting, cough etc.Timepoint: 1. severity sore throat was assessed at 0, 2, 4, 24 hrs post-operatively 2. oropharyngeal trauma at removal of Proseal Proseal 3.side effects post operatively

Primary

MeasureTime frame
1. incidence of post-operative sore throatTimepoint: 1. sore throat was assessed at 0, 2, 4, 24 hrs post-operatively

Countries

India

Contacts

Public ContactSIVARAM P

Maulana azad medical college

dr_dali@rediffmail.com9789725150

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026