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Change in BLOOD PRESSURE and HEART RATE while doing laryngoscopy and intubation

A comparative study of hemodynamic responses to intubation : fentanyl versus nalbuphine

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2017/06/008835
Enrollment
60
Registered
2017-06-14
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K00-K95- Diseases of the digestive system Health Condition 2: H60-H95- Diseases of the ear and mastoid process Health Condition 3: N00-N99- Diseases of the genitourinary system Health Condition 4: M00-M99- Diseases of the musculoskeletal system and connective tissue Health Condition 5: G00-G99- Diseases of the nervous system Health Condition 6: J00-J99- Diseases of the respiratory system Health Condition 7: E00-E89- Endocrine, nutritional and metabolic diseases Health Conditi

Interventions

Intervention1: NALBUPHINE: Fentanyl was first synthesized in 1960 and found to be significantly more potent than commonly used opioids, such as morphine or meperidine. The large safety margin, relativ

Sponsors

Department of Anaethesia
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.AMERICAL SOCIETY OF ANESTHESIOLOGY PHYSICAL STATUS GRADE 1 & 2 2.WEIGHT BETWEEN 20-80 KG 3.Patients planned for surgery under general anaesthesia and requiring Laryngoscopy and Orotracheal Intubation in tertiary care hospital

Exclusion criteria

Exclusion criteria: 1.AMERICAL SOCIETY OF ANESTHESIOLOGY PHYSICAL STATUS GRADE MORE THAN 2 2.History of Hypertension, Diabetes, Cardiac disease, Bronchospastic Diseases 3.Patients on Beta Blockers 4.History of allergy to trial drugs 5.Emergency Surgeries , Difficult intubations

Design outcomes

Primary

MeasureTime frame
1.To study the effect of I.V Fentanyl and I.V Nalbuphine during laryngoscopy and intubation on Heart rate (HR) Systolic blood pressure SBP Diastolic blood pressure DBP 2. To compare side effects and complications of both drugs.Timepoint: 2 Years

Secondary

MeasureTime frame
To compare side effects and complications of both drugs.Timepoint: 2 Years

Countries

India

Contacts

Public ContactKRUNAL

Armed Forces Medical College

krunalbhatt1@gmail.com7798650722

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026