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Effect of two types of weight loss procedures on development of gastro-esophageal reflux.

Prospective Clinical Trail comparing Effects of Sleeve gastrectomy and Roux en Y gastric bypass on denovo development of GERD in terms of clinical, physiological, anatomical and histopathological changes.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2017/06/008834
Enrollment
30
Registered
2017-06-14
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Obesity Health Condition 2: E669- Obesity, unspecified

Interventions

Intervention1: Laparoscopic sleeve gastrectomy: Creation of stomach tube over a 37.6 Fr bougie by sequential firing of linear staplers, a type of restrictive procedure for morbid obesity Control Inter

Sponsors

GEM Hospital and Research Centre
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Obese individuals with BMI more than 30 Kg/m2

Exclusion criteria

Exclusion criteria: Presence of GERD determined by DeMeester score more than 15 Presence of hiatus hernia Revisional bariatric surgery Previous history of upper GI surgery

Design outcomes

Primary

MeasureTime frame
Incidence of denovo GERD as measured by 24 hour pH study with DeMeesters score of more than 15Timepoint: 6 months 12 months—

Secondary

MeasureTime frame
Co-morbidities resolutionTimepoint: 6 months;Incidence of denovo GERD by GERD questionnaireTimepoint: 6 months;Incidence of denovo GERD by histopathological examination of endoscopic biopsyTimepoint: 6 months;Incidence of denovo GERD by impedence manometryTimepoint: 6 months;Incidence of denovo GERD by upper GI endoscopyTimepoint: 6 months;Manometric changes in esophageal motilityTimepoint: 6 months;Weight lossTimepoint: 6 months—

Countries

India

Contacts

Public ContactP Praveen Raj

GEM Hospital and Research centre

drraj@geminstitute.in9894200200

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 3, 2026