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Comparison of 3 drugs in treating low back pain with lower limb pain

comparative study of safety and efficacy of pregabalin, gabapentin and amitriptyline in management of neuropathic pain associated with chronic lumbar radiculopathy

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2017/06/008812
Enrollment
72
Registered
2017-06-12
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- CHRONIC LUMBAR RADICULOPATHY

Interventions

Control Intervention1: pregabalin , gabapentin , amitriptyline: three groups . group A will be given pregabalin 75 mg bid , group B will be given gabapentin 300 mg bid, group C will be given amitripty

Sponsors

NONE
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patient willing to participate in the study. 2.Age group of 18-65 years of either sex. 3.Diagnosed cases of chronic lumbar radiculopathy based on symptoms, clinical examination, x-ray and MRI scan of lumbosacral spine. 4.Patients who have not taken the study drugs previously.

Exclusion criteria

Exclusion criteria: 1.pregnant and lactating women 2.immunocompromized patients 3.history of diabetes and tuberculosis 4.history of cardiac illness 5.history of renal and liver disease 6.patients taking anticholinergics and antipsychotic medicines 7.history of psychiatric disorders 8.patients having neurodeficit in lower limb 9. patients with bladder and bladder incontinence 10.radiculopathy secondary to tumors 11.patients with known hypersensitivity to trial drugs.

Design outcomes

Primary

MeasureTime frame
reduction of intensity of neuropathic painTimepoint: At the end of 6 weeks and 12 weeks

Secondary

MeasureTime frame
change in mean pain score from baseline to end pointTimepoint: At the end of 6 weeks and 12 weeks

Countries

India

Contacts

Public ContactDR HUZAIF B SHAIKH

MGMs medical college, Aurangabad

huzaifshaikh001@gmail.com9049484204

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026