None listed
Conditions
Interventions
Intervention1: Agomelatine: tablet agomelatine 25 mg single dose compared with identical placebo
Sponsors
Dr G Sirisha
Eligibility
Inclusion criteria
Inclusion criteria: Twelve healthy adult volunteers aged between 18 to 25 years, with BMI of 18.5 to 24.9 Kg/m2were enrolled in the study. Subjects who were able to comprehend and perform the tests and atleast completed their primary education were included in the study.
Exclusion criteria
Exclusion criteria: Exclusion criteria included those with hypertension, hyperglycemia, impaired hepatic or renal function, and cardiac arrhythmia, history of smoking, chronic alcoholism, malignancy or stroke, on benzodiazepines and neuroleptics abuse, any disease requiring active treatment or with herbal supplements.Subjects having history of hypersensitivity, mental illness, history of occupation with machinery or driving, those who were unwilling to participate were also excluded
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| effect of agomelatine on different psychomotor function testsTimepoint: single time point at the end of tests | — |
Secondary
| Measure | Time frame |
|---|---|
| adverse drug reactions with agomelatine were analysedTimepoint: single time point at the end of tests | — |
Countries
India
Contacts
Public ContactG Sirisha
Nizams institute of medical sciences.
Outcome results
None listed