Health Condition 1: C50- Malignant neoplasm of breast
Conditions
Interventions
None listed
Sponsors
M S Yamuna devi
K Bhuvaneswari
Eligibility
Inclusion criteria
Inclusion criteria: 1.All Ca breast patients on AC/T regimen â??diagnosed based on AJCC staging criteria, belonging to Stage I, Stage II, Stage III 2.All these 3 groups with laboratory parameters between normal limit to upper limit of contraindicated values
Exclusion criteria
Exclusion criteria: 1.Patients who were on other chemotherapy regimens previously 2.Tumor beyond stage IV 3.Patients with co morbid conditions like renal failure, liver failure and cardiac problems
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| abnormalities in the liver and renal function tests (less than the lower limit or more than the upper limit of normal)correlated with the plasma concentrations of Adriamycin, Cyclophosphamide and Paclitaxel analysed through HPLCTimepoint: at the third cycle of AC/T regimen | — |
Secondary
| Measure | Time frame |
|---|---|
| clinical reduction (%) in tumour size correlated with the plasma concentrations of Adriamycin, Cyclophosphamide and Paclitaxel analysed through HPLCTimepoint: at the third cycle of AC/T regimen;corelation of estrogen and progesterone receptors with plasma concentrations of Adriamycin, Cyclophosphamide and Paclitaxel and related ADRs in patients with Ca breast Timepoint: at the third cycle of AC/T regimen | — |
Countries
India
Contacts
Public ContactM S Yamuna devi
PSG Institute of Medical Sciences and Research
Outcome results
None listed