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comparing intraartcular ropivacaine with intraarticualr dexmedetomidine orcombination of both

Comparative evaluation of intra-articular ropivacaine, dexmedetomidine and combination of ropivacaine-dexmedetomidine on postoperative analgesia after arthroscopic knee surgery

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2017/06/008762
Enrollment
108
Registered
2017-06-05
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- ASA I and II

Interventions

Intervention1: Group R:-intraartular administration of ropivacaine 0.5% (20ML): In group R, 19 ml of 0.5% ropivacaine and 1 ml isotonic saline (total volume 20 ml) will be administered into the knee j

Sponsors

Government Medical College Jammu
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: After the ethic committeeâ??s approval, informed written consents were obtained from 108 patients, ASA physical status Iâ??II, age between 18 and 65, scheduled to undergo elective arthroscopic knee surgery.

Exclusion criteria

Exclusion criteria: Exclusion criteria included Patient refusal, any known allergy or contraindication to ropivacaine, or dexmedetomidine, pregnancy, lactating mothers and children, hepatic, renal or cardiopulmonary abnormality, long-term analgesic therapy, spinal cord deformities, bleeding diathesis, local skin site infections , and morbid obesity (body mass index > 35)..

Design outcomes

Primary

MeasureTime frame
Duration of effective analgesia will be measured from time of completion of surgery until first requirement of rescue analgesic.Timepoint: time of first analgesic request as the main primary variable

Secondary

MeasureTime frame
. VAS pain scores will be recorded at rest and on movement (90° flexion of the operated knee). total diclofenac and tramadol use during the first 24 postoperative hours will be also recordedTimepoint: ist 24 hours postoperatively

Countries

India

Contacts

Public ContactRajesh Mahajan

GMC , JAMMU

drmahajanr@rediffmail.com09419141263

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026