Health Condition 1: null- Knee osteoarthritis
Conditions
Interventions
Intervention1: hylan g-f 20, dextrose, ozone, dextrose with ozone: high molecular weight hylan g-f 20
6 ml intra-articular once
dextrose
12.5% 10 ml intra-articular once per week for 5 weeks
ozone
15
Sponsors
ESI Institute of Pain Management
Eligibility
Inclusion criteria
Inclusion criteria: Pain in the knee Kellgren â?? Lawrence grade I,II,III on PA knee radiograph, and grade IV not willing to surgery Age 50 to 75 years. Any THREE of the following: a) Less than 30 minutes of morning stiffness. b) Crepitus on active movement. c) Bony tenderness. d) Bony enlargement. e) No palpable warmth of synovium.
Exclusion criteria
Exclusion criteria: Systemic disease On anticoagulants Knee pain/ swelling due to inflammation, infection etc. Previous intra articular injection. Use of opioid analgesics. Intra articular fluid accumulation. Patients taking opioid analgesics.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain in Numeric Rating Scale ScoreTimepoint: Day 0 and 2 months after the completion of treatment course | — |
Secondary
| Measure | Time frame |
|---|---|
| function by Western Ontario and McMaster University Arthritis Index (WOMAC) scoreTimepoint: day 0 and 2 months after completion of treatment course;Joint space in standing Xray of affected knee jointTimepoint: day 0 and 2 months after the completion of treatment course | — |
Countries
India
Contacts
Public ContactDr Subrata Goswami
ESI Institute of Pain Management
Outcome results
None listed