Health Condition 1: null- Chronic Drug Resistant Mesial Temporal Lobe Epilepsy Health Condition 2: G328- Other specified degenerative disorders of nervous system in diseases classified elsewhere
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.People with chronic drug resistant mesial temporal lobe epilepsy 2.A radiological diagnosis of MTS 3.Willing for surgery and the study
Exclusion criteria
Exclusion criteria: Drug resistant neo-cortical, temporal plus or extra- temporal lobe epilepsy No MTS on MRI or having neoplastic and vascular lesions Not willing for the surgery/study Previously operated cases
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Increase in the hippocampal volume and improvement in the memory and IQ in the intervention group compared to the control groupTimepoint: 3 months preoperative, per operative and 6 months post operatively | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Improvement in the heart rate variability 2.Decrease in the inflammatory markers in the intervention group compared to the control groupTimepoint: 1.3 months preoperative 2.per operative 3.6 months post operatively | — |
Countries
India
Contacts
National Institute of Mental Health & Neuro Sciences (NIMHANS)