Effect of mouth wash of Clerodendrum infortunatum against plaque and gum inflammation

Effect of Clerodendrum infortunatum and control (placebo) mouth wash formulations in dental plaque and gingivitis patients: A randomized double blind control Clinical trial

Status

Recruiting

Phases

Phase 1Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2017/05/008693

Enrollment

Registered

2017-05-29

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Patients havening plaque and gingivitis from mild to moderate and there is no serious issue of any health conditions.

Interventions

Intervention1: Intervention â??Mouth wash of Clerodendrum infortunatum: 21 days: Mouth wash of Clerodendrum infortunatum formulation will be dispensed in the form mouth wash. 5ml will be swished for 6

Eligibility

Inclusion criteria

Inclusion criteria: 1.Subjects have ability to understand and sign a consent form prior to the recruitment on the study. 2.Healthy patients 18-30years 3.Subjects with mild to moderate gingivitis Marginal Index score >1.75 and Plaque Index >2.4. 4.Minimum 20 teeth should be present in the dentition, no visble sign of untreated caries. 5.Patient diagnosed with mild to moderate type of gingivitis. 6.Generally good health (no sign of periodontitis , no active caries and no soft tissue lesions, patient on any antibiotics therapy) 7.Patientâ??s ability and willingness of subjects follow the study procedures and. attend all scheduled visits and successfully complete the study.

Exclusion criteria

Exclusion criteria: 1.Subjects taking antibiotics or any other drugs within last 3 months. 2.Pregnant women and lactating women. 3.Medically compromised patients 4.Patients have periodontitis and active caries 5.Patients with a know history of allergic to chemical or any herbal product 6.Smokers and compulsive tobacco chewers

Design outcomes

Primary

Measure	Time frame
Reduction in the Gingivitis scores. Intial scores of Modified Gingival Index(Lobene), Bleeding index (saxton and van der ouderaa) compared to scores after 4 weeks. Interval of scores: 0 day, 9nd day 15th day and 30th day. Timepoint: Reduction in the Gingivitis scores. Plaque ondex (Modified Quigley Hein Plaque Index) compared to scores after 4 weeks. Interval of score : 0 day, 9nd day,15th day and 30th day.	—

Measure

Time frame

Reduction in the Gingivitis scores. Intial scores of Modified Gingival Index(Lobene), Bleeding index (saxton and van der ouderaa) compared to scores after 4 weeks. Interval of scores: 0 day, 9nd day 15th day and 30th day. Timepoint: Reduction in the Gingivitis scores. Plaque ondex (Modified Quigley Hein Plaque Index) compared to scores after 4 weeks. Interval of score : 0 day, 9nd day,15th day and 30th day.

—

Secondary

Measure	Time frame
Reduction in the Plaque index Timepoint: Plaque Index (Modified Quigley Hein Plaque Index) compared to scores after 4 weeks Interval of score: 0 day, 9rd day, 15th day and 30th day	—

Countries

India

Contacts

Public ContactDr Shivaraj Warad

PMNM Dental College and Hospital

shivwarad@gmail.com08354220435

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026