Health Condition 1: null- Patients with diabetic keto aciodosis
Conditions
Interventions
Control Intervention1: Capillary beta-hydroxybutyrate: measured using Abbott optium ketone strips
Control Intervention2: Serum beta-hydroxybutyrate: measured using colorimetric method kits
Sponsors
JIPMER intramural fund
Eligibility
Inclusion criteria
Inclusion criteria: All children less than 12 years of age with diabetic ketoacidosis admitted in emergency department
Exclusion criteria
Exclusion criteria: 1. Children with suspected or known inborn errors of metabolism. 2. Patients identified as having septic shock, i.e., patients requiring more than 60 ml/kg bolus fluids or vasoactive treatment during initial resuscitation in emergency department.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.Capillary beta hydroxybutyrate 2.Serum beta hydroxybutyrateTimepoint: 1.measured by electrochemical methods every 2 hourly for first 6 hours and 6 hourly thereafter till resolution of diabetic ketoacidosis 2. measured by colorimetric method every 2 hourly for first 6 hours and 6 hourly thereafter till resolution of diabetic ketoacidosis | — |
Secondary
| Measure | Time frame |
|---|---|
| Correlation between beta hydroxybutyrate and blood glucoseTimepoint: measured every 2 hourly for first 6 hours and 6 hourly thereafter till resolution of diabetic ketoacidosis;Correlation between beta hydroxybutyrate and blood pHTimepoint: measured every 2 hourly for first 6 hours and 6 hourly thereafter till resolution of diabetic ketoacidosis;Correlation between betahydroxybutyrate and serum bicarbonate levelsTimepoint: measured every 2 hourly for first 6 hours and 6 hourly thereafter till resolution of diabetic ketoacidosis | — |
Countries
India
Contacts
Public ContactDr Praveen M Kurup
JIPMER (Jawaharlal institute of post-graduate medical education and research)
Outcome results
None listed