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Cognitive recovery from general anesthetics in electroconvulsive therapy

Effect of general anaesthetic agents on cognitive recovery in patients undergoing electroconvulsive therapy

Status
Active, not recruiting
Phases
Phase 4
Study type
Observational
Source
CTRI
Registry ID
CTRI/2017/05/008674
Enrollment
70
Registered
2017-05-26
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Psychiatric patients suffering from Major depression disorder, Bipolar Mood disorder,Schizophrenia,Schizoaffective disorders

Interventions

Intervention1: Injection Propofol: Effect of General Anaesthetic Agents on Cognitive Recovery in Patients undergoing Electroconvulsive Therapy. Control Intervention1: Injection Thiopentone Sodium : E

Sponsors

Lokmanya Tilak Municipal Medical General HospitalSion Mumbai
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with major depression disorder, bipolar mood disorder,schizophrenia and schizoaffective disorder.

Exclusion criteria

Exclusion criteria: Patients 60yrs. Patients with history of hypertension, diabetes mellitus, epilepsy, coronary artery disease. Patients with anticipated difficult intubation. Patients not meeting fasting guidelines. Patients having problems in communication due to hearing problem,language barrier. Pregnant and lactating females

Design outcomes

Primary

MeasureTime frame
To evaluate the effect of general anaesthetic agents on degree of cognitive recovery after electroconvulsive therapy and will be measured by Mini Mental Score ExaminationTimepoint: Mini Mental State Examination of patients will be done one hour after ECT

Secondary

MeasureTime frame
To evaluate the effects of general anaesthetic agents on seizure duration,seizure threshold effect on cardiorespiratory parameters and recovery from the effects of general anaesthetic agents.Timepoint: Seizure thresholds the time of delivery of electric stimulus. Seizure duration - after application of electric stimulus. Heart rate,ECG, NIBP, SPO2-Every minute during ECT and five minutes to after recovery. Time to breathe and eye opening after cessation seizures.

Countries

India

Contacts

Public ContactDrShailendra Modak

Lokmanya Tilak Municipal Medical General Hospital,Sion,Mumbai

shailendramodak@yahoo.com9320329229

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026