Role of Vitamin D treatment in women with multiple cysts in ovary(reproductive organ) who have low vitamin D blood levels

Effect of Vitamin D as Add-on Therapy in Vitamin D Deficient Women with Polycystic Ovary Syndrome: A Randomized Double Blind Placebo Controlled Trial.

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2017/05/008667

Enrollment

122

Registered

2017-05-25

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Polycystic ovary syndrome patients with vitamin D deficiency

Interventions

Intervention1: Vitamin D: Tablet Vitamin D 60,000 IU / week for 2 months in addition to Standard background therapy Control Intervention1: Placebo: Similar looking placebo tablet once weekly for 2 mo

Eligibility

Inclusion criteria

Inclusion criteria: Overweight (BMI > 23 kg/m2) and Vitamin D deficient ( < 20 ng/ml) PCOS women diagnosed by Rotterdamâ??s criteria

Exclusion criteria

Exclusion criteria: PCOS patients with co-morbid conditions like uncontrolled hypertension, untreated hypo or hyperthyroidism, diabetes mellitus or any endocrinopathy Patients already on vitamin D or calcium supplements Pregnant or lactating women PCOS patients with clinical symptoms and signs of vitamin D deficiency and with vitamin D levels less than 10 ng/ml

Design outcomes

Primary

Measure	Time frame
OGTT,Lipid profile, Fasting plasma insulin (HOMA-IR),Serum testosterone levels Timepoint: At baseline and after 2 months	—

Secondary

Measure	Time frame
Clinical features of hyperandrogenismTimepoint: At baseline and after 2 months	—

Countries

India

Contacts

Public ContactDr Jayaprakash Sahoo

JIPMER

drsmanikandan001@gmail.com9443774648

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026